Louise Sigfrid is our Clinical Research Fellow.

Louise’s main focus is the PREPARE (Platform for European Preparedness Against (Re-) emerging Epidemics) project. She studies incidence risk factors and clinical impact of infections with epidemic potential in Europe with a focus on acute respiratory infections, central nervous system infections, arbovirus and haemorrhagic fever syndromes in hospitalized and primary care patients.

Selected Publications

Sigfrid L, Moore C, Salam A, Maayan N, Hamel C, Garritty C, Lutje V, Buckley B, Soares-Weiser K, Marshall R, Clarke M, Horby P. A rapid research needs appraisal methodology to identify evidence gaps to inform clinical research priorities in response to outbreaks—results from the Lassa fever pilot. BMC Medicine. 2019 June 11, 17:107. doi:10.1186/s12916-019-1338-1. Read more.

Gobat N, Amuasi J, Yazdanpanah Y, Sigfrid L, Davies H, Byrne JP, Carson G, Butler C, Nichol A, Goossens H. Advancing preparedness for clinical research during infectious disease epidemics. ERJ Open Res. 2019 Apr; 5(2): 00227-2018. doi: 10.1183/23120541.00227-2018. Read more.

Gobat N, Van Someren Greve F, Sigfrid L, Reusken C, Degee F, Carson G, Horby P, Koopmans M, De Jong M, Goossens H. Preparedness for clinical research during pandemics: a perspective from the Platform for European Preparedness Against (Re-) emerging Epidemics (PREPARE) in Europe. Lancet. 2018 Nov; 392 (2): S38. doi: 10.1016/S0140-6736(18)32099-3. Read abstract | Read more.

Eckerle I, Briciu VT, Ergönül Ö, Lupşe M, Papa A, Radulescu A, Tsiodras S, Tsitou C, Drosten C, Nussenblatt VR, Reusken CB, Sigfrid LA, Beeching NJ. Emerging souvenirs-clinical presentation of the returning traveller with imported arbovirus infections in Europe. Clin Microbiol Infect. 2018 Mar;24(3):240-245. doi: 10.1016/j.cmi.2018.01.007. Read abstract | Read more.

Sigfrid L, Eckerle I, Papa A, Horby P, Koopmans M, Reusken C. Strengthening perparedness for (re-)emerging arboviruses in Europe. Clin Microbiol Infect. 2018 Mar; 24 (3):219-220. doi: 10.1016/j.cmi.2018.02.001. Read more.

Reusken CB, Ieven M, Sigfrid L, Eckerle I, Koopmans. Laboratory Preparedness and Response with a focus on Arboviruses in Europe. Clin Microbiol Infect. 2017 Dec 20. pii: S1198-743X(17)30683-3. doi: 10.1016/j.cmi.2017.12.010. Read abstractRead more.

Watt N, Sigfrid L, Legido-Quigley H, Hogarth S, Maimaris W, Otero-García L, Perel P, Buse K, McKee M, Piot P, Balabanova D. Health systems facilitators and barriers to the integration of HIV and chronic disease services: a systematic review. Health Policy Plan. 2017 Nov 1;32(suppl_4):iv13-iv26. doi: 10.1093/heapol/czw149. Read abstract Read more.

Sigfrid L, Murphy G, Haldane V, Chuah FLH, Ong SE, Cervero-Liceras F, Watt N, Alvaro A, Otero-Garcia L, Balabanova D, Hogarth S, Maimaris W, Buse K, Mckee M, Piot P, Perel P, Legido-Quigley H. Integrating cervical cancer with HIV healthcare services: A systematic review. PLoS One. 2017 Jul 21;12(7):e0181156. doi: 10.1371/journal.pone.0181156. eCollection 2017. Read abstractRead moree.

Sigfrid L, Reusken C, Eckerle I, Nussenblatt V, Lipworth S, Messina J, Kraemer M, Ergonul O, Papa A, Koopmans M, Horby P. Preparing clinicians for (re-)emerging arbovirus infectious diseases in Europe. Clin Microbiol Infect. 2017 Jun 23. Clin Microbiol Infect. 2017 Jun 23. pii: S1198-743X(17)30336-1. doi: 10.1016/j.cmi.2017.05.029.  Read abstractRead more.

Wolfe I, Sigfrid L, Chanchiani N, Lenton S. Child Health Systems in the United Kingdon (England). J Pediatr. 2016 Oct;177S:S217-S242. doi: 10.1016/j.jpeds.2016.04.058. Epub 2016 Sep 22. Read abstractRead more.

Sigfrid L, Reusken C, Carson G, Koopmans M. Zika: structuring the European research response. ERJ Open Res. 2016 Mar 17;2(1). pii: 00025-2016. eCollection 2016 Jan. Read abstractRead more.