Coordinated by the European-funded PREPARE network and supported by ERGO, MERMAIDS (The Multi-centre EuRopean study of MAjor Infectious Disease Syndromes) has now closed recruitment for three of its studies on acute respiratory infection, arboviral compatible febrile illness, and Sepsis-like syndrome in infants and ARI in children. 1524 patients were recruited for the ARI study, over 900 for the ARBO study and 705 for the pediatric study . A huge congratulations to all of the sites across Europe who worked with ERGO and PREPARE teams to achieve this fantastic result, particularly in MERMAIDS-ARI which represents the largest ever study of the pathogenesis of ARI.  All sites promise exciting insights in the coming months and years.

Ribavirin Healthy Volunteers Study Open

Our Ribavirin Healthy Volunteers Study is now open for recruitment! The aim of the study is to validate a method of measuring a drug called ribacirin in the blood. Ribavirin is normally used to treat Hepatitis C and other diseases such as Lassa fever, which is a viral infection occuring in West Africa.

Volunteers will be compensated for their time. For more information, see


A rapid research needs appraisal methodology to identify evidence gaps to inform clinical research priorities in response to outbreaks—results from the Lassa fever pilot

by Louise Sigfrid, Alex Salam and Peter Horby

  BMC Medicine 2019 17:107 Louise Sigfrid, Catrin Moore, Alex P. Salam, Nicola Maayan, Candyce Hamel, Chantelle Garritty, Vittoria Lutje, Brian Buckley, Karla Soares-Weiser, Rachel Marshall, Mike Clarke and Peter Horby Infectious disease epidemics are a constant threat, and while we ...