Peter Horby is Professor of Emerging Infectious Diseases and Global Health. He is the former, and founding Director of the Oxford University Clinical Research Unit in Hanoi, Vietnam. Established in early 2006, the unit conducts research on infectious diseases which crosses the disciplines of basic science, medical science and public health.
Peter returned to Oxford in July 2014 and established the Epidemic diseases Research Group Oxford (ERGO). ERGO is engaged in an international program of clinical and epidemiological research to prepare for and respond to emerging infections that may develop into epidemics or pandemics. ERGO is involved in a number of international projects including the European Commission funded PREPARE and ALERRT projects, the International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) and the UK Public Health Rapid Support Team (UK-PHRST). The group is conducting research on a range of epidemic diseases including Ebola virus disease, bird flu (H5N1 and H7N9), MERS-CoV, and Enterovirus 71. ERGO currently comprises a team of eleven people under the leadership of Professor Peter Horby and is funded by the Wellcome Trust, the Medical Research Council, the European Commission and the Department of Health and Social Care.
In June 2016, Peter became Chair of ISARIC, taking over from outgoing Chair Abdullah Brooks.
Rojek AM, Salam A, Ragotte RJ, Liddiard E, Elhussain A, Carlqvist A, Butler M, Kayem N, Castle L, Odondi L, Stepniewska K, Horby PW. A systematic review and meta-analysis of patient data from the west Africa (2013-16) Ebola virus disease epidemic. Clin Microbiol Infect. 2019 Jul 5. doi: 10.1016/j.cmi.2019.06.032. Read abstract | Read more.
Sigfrid L, Moore C, Salam A, Maayan N, Hamel C, Garritty C, Lutje V, Buckley B, Soares-Weiser K, Marshall R, Clarke M, Horby P. A rapid research needs appraisal methodology to identify evidence gaps to inform clinical research priorities in response to outbreaks—results from the Lassa fever pilot. BMC Medicine. 2019 June 11, 17:107. doi:10.1186/s12916-019-1338-1. Read more.
Saxena A, Horby P, Amuasi J, Aagaard N, Köhler J, Gooshki ES, Denis E, Reis AA, the ALERRT-WHO Workshop and Ravinetto R. Ethics preparedness: facilitating ethics review during outbreaks - recommendations from an expert panel. BMC Medical Ethics. 2019 May 6, 20:29. doi:10.1186/s12910-019-0366-x. Read more.
Wang Y, Fan G, Horby P, Hayden F, Li Q, Wu Q, Zou X, Li H, Zhan Q, Wang C, Cao B; CAP-China Network. Comparative Outcomes of Adults Hospitalized With Seasonal Influenza A or B Virus Infection: Application of the 7-Category Ordinal Scale. Open Forum Infectious Diseases. 2019 Feb 15;6(3):ofz053. doi: 10.1093/ofid/ofz053. eCollection 2019 Mar. Read abstract | Read more.
Battista MC, Loignon C, Benhadj L, Nouvet E, Murthy S, Fowler R, Adhikari NKJ, Haj-Moustafa A, Salam AP, Chan AK, Mishra S, Couturier F, Hudon C, Horby P, Bedell R, Rekart M, Hajek J, Lamontagne F. Priorities, barriers, and facilitators towards international guidelines for the delivery of supportive clinical care curing an Ebola outbreak: a cross-sectional survey. Viruses. 2019 Feb. doi: 10.3390/v11020194. Read more.
Rampling T, Page M, Horby P. International Bipological Reference Preparations for Epidemic Infectious Diseases. Emerging Infectious Diseases. 2019 Feb. doi:10.3201/eid2502.180798. Read more.
Murthy S, Carson G, Horby P, Merson L, Webb S. Clinical research networks and assessing pandemic severity. The Lancet. 2019 Jan. doi: 10.1016/S2214-109X(18)30413-3. Read more.
Brueckner M, Titman A, Jaki T, Rojek A, Horby P. Performance of different clinical trial designs to evaluate treatments during an epidemic. PLoS one. 2018 Sep 11. doi: 10.1371/journal.pone.0203387. Read abstract | Read more.
Horby, PW. Improving preparedness for the next flu pandemic. Nat Microbiol. 2018 Aug;3(8):848-850. doi: 10.1038/s41564-018-0206-7. Read more.
Zhao M, Chen J, Tan S, Dong T, Jiang H, Zheng J, Quan C, Liao Q, Zhang H, Wang X, Wang Q, Bi Y, Liu F, Feng L, Horby PW, Klenerman P, Gao GF, Liu WJ, Yu H. Prolonged Evolution of Virus-Specific Memory T Cell Immunity after Severe Avian Influenze A (H7N9) Virus Infection. J Virol. 2018 Aug 16;92(17). pii: e01024-18. doi: 10.1128/JVI.01024-18. Read abstract | Read more.
Wang X, Wu P, Pei Y, Tsang TK, Gu D, Wang W, Zhang J, Horby PW, Uyeki TM, Cowling BJ, Yu H. Assessment of human-to-human transmissibility of avian influenza A(H7N9) virus across five waves by analyzing clusters of case-patients in mainland China, 2013-2017. Clin Infect Dis. 2018 Jun 29. doi: 10.1093/cid/ciy541. Read abstract | Read more.
Gao L, Zou G, Liao Q, Zhou Y, Liu F, Dai B, Liu J, Chen Z, Xing W, Yang L, Liang H, Zhang Y, Chen Z, Luo L, Li Q, Luo K, Wu P, Mo X, Wang L, Lan K, Horby PW, Cowling BJ, Simmonds P, Altmeyer R, van Doorn HR, Yu H. Spectrum of Enterovirus Serotypes Causing Uncomplicated Hand, Foot, and Mouth Disease and Enteroviral diagnostic yield of different clinical samples. Clin Infect Dis. 2018 Apr 24. doi: 10.1093/cid/ciy341. Read abstract | Read more.
Rojek AM, Gkolfinopoulou K, Veizis A, Lambrou A, Castle L, Georgakopoulou T, Blanchet K, Panagiotopoulos T, Horby PW. Clinical assessment is a neglected component of outbreak preparedness: evidence from refugee camps in Greece. BMC Medicine. 2018 Apr; 16:43. doi: 10.1186/s12916-018-1015-9. Read abstract | Read more.
Sigfrid L, Eckerle I, Papa A, Horby P, Koopmans M, Reusken C. Strengthening perparedness for (re-)emerging arboviruses in Europe. Clin Microbiol Infect 2018 Mar; 24 (3):219-220. doi: 10.1016/j.cmi.2018.02.001. Read more.
Salam AP, Horby PW. Isolation of viable Zika virus from spermatozoa. The Lancet Infectious Diseases. 2018 Feb. doi: 10.1016/S1473-3099(18)30020-3. Read more.
Sigfrid L, Reusken C, Eckerle I, Nussenblatt V, Lipworth S, Messina J, Kraemer M, Ergonul O, Papa A, Koopmans M, Horby P. Preparing clinicians for (re-) emerging arbovirus infectious diseases in Europe. Clin Microbiol Infect. 2017 Jun 22. pii: S1198-743X(17)30336-1. doi: 10.1016/j.cmi.2017.05.029. Review. Read Abstract | Read More
Wang X, Jiang H, Wu P, Uyeki TM, Feng L, Lai S, Wang L, Huo X, Xu K, Chen E, Wang X, He J, Kang M, Zhang R, Zhang J, Wu J, Hu S, Zhang H, Liu X, Fu W, Ou J, Wu S, Qin Y, Zhang Z, Shi Y, Zhang J, Artois J, Fang VJ, Zhu H, Guan Y, Gilbert M, Horby PW, Leung GM, Gao GF, Cowling BJ, Yu H. Epidemiology of avian influenza A H7N9 virus in human beings across five epidemics in mainland China, 2013-17: an epidemiological study of laboratory-confirmed case series. Lancet Infect Dis. 2017 Aug;17(8):822-832. doi: 10.1016/S1473-3099(17)30323-7. Epub 2017 Jun 2. Read abstract | Read More
Laxminarayan R, Kakkar M, Horby P, Malavige GN, Basnyat B. Emerging and re-emerging infectious disease threats in South Asia: status, vulnerability, preparedness, and outlook. BMJ. 2017 Apr 11;357:j1447. doi: 10.1136/bmj.j1447. Review.
Rojek AM, Horby PW. Offering patients more: how the West Africa Ebola outbreak can shape innovation in therapeutic research for emerging and epidemic infections. Philos Trans R Soc Lond B Biol Sci. 2017 May 26;372(1721). pii: 20160294. doi: 10.1098/rstb.2016.0294. Review. Read Abstract | Read More
Lee N, Cao B, Ke C, Lu H, Hu Y, Tam CHT, Ma RCW, Guan D, Zhu Z, Li H, Lin M, Wong RYK, Yung IMH, Hung TN, Kwok K, Horby P, Hui DSC, Chan MCW, Chan PKS.IFITM3, TLR3, and CD55 Gene SNPs and Cumulative Genetic Risks for Severe Outcomes in Chinese Patients With H7N9/H1N1pdm09 Influenza. J Infect Dis. 2017 Jul 1;216(1):97-104. doi: 10.1093/infdis/jix235. Read Abstract | Read More
Rojek A, Horby P, Dunning J. nsights from clinical research completed during the west Africa Ebola virus disease epidemic. Lancet Infect Dis. 2017 Sep;17(9):e280-e292. doi: 10.1016/S1473-3099(17)30234-7. Epub 2017 Apr 28. Review. Read Abstract | Read More
Salam AP, Rojek A, Dunning J, Horby PW. Clinical trials of therapeutics for the prevention of congenital Zika virus disease: challenges and potential solutions.Ann Intern Med. 2017 Mar 21. doi: 10.7326/M16-2530. [Epub ahead of print] Read Abstract | Read More
Whitehead J, Horby P. GOST: A generic ordinal sequential trial design for a treatment trial in an emerging pandemic.PLoS Negl Trop Dis. 2017 Mar 9;11(3):e0005439. doi: 10.1371/journal.pntd.0005439. eCollection 2017 Mar 9. Read Abstract | Read More
Journal article) Read AbstractJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology 82:126-132 Sep 2016 (
The Pediatric infectious disease journal 35(10):e285-e300 Oct 2016 (Journal article) Read Abstract
Journal article) Read AbstractThe Lancet. Infectious diseases 16(7):e108-e118 Jul 2016 (
Journal article) Read AbstractJournal of virology 90(14):6549-6556 Jul 2016 ( Teaching research methodology within an Ebola virus outbreak. Medical education 50(5):584-585 May 2016 (
Horby PW, Rojek A. 2016. Modernising epidemic science: enabling patient-centred research during epidemics. BMC Medicine. 2016:14:12. DOI: 10.1186/s12916-016-0760-x Read Abstract
Dunning J, Sahr F, Rojek A, Gannon F, Carson G, Idriss B, Massaquoi T, Gandi R, Joseph S, Osman HK, Brooks TJ, Simpson AJ, Goodfellow I, Thorne L, Arias A, Merson L, Castle L, Howell-Jones R, Pardinaz-Solis R, Hope-Gill B, Ferri M, Grove J, Kowalski M, Stepniewsdka K, Lang T, Whitehead J, Olliaro P, Samai M, Horby PW; RAPIDE-TKM Trial Team. 2016. Experimental Treatment of Ebola Virus Disease with TKM-130803: A Single-Arm Phase 2 Clinical Trial. PLoS Med. 2016 Apr 19;13(4):e1001997. doi: 10.1371/journal.pmed.1001997. Read Abstract
Whitehead J, Olliaro P, Lang T, Horby P. 2016. Trial design for evaluating novel treatments during an outbreak of an infectious disease. Clin Trials. 2016 Feb;13(1):31-8. doi: 10.1177/1740774515617740. Epub 2016. Read Abstract | Read more
Lancet, 371 (9622), pp. 1392-1394. | Read more2008. Person-to-person transmission of influenza A (H5N1).