Peter Horby is Professor of Emerging Infectious Diseases and Global Health.  He is the former, and founding Director of the Oxford University Clinical Research Unit in Hanoi, Vietnam. Established in early 2006, the unit conducts research on infectious diseases which crosses the disciplines of basic science, medical science and public health.

Peter returned to Oxford in July 2014 and established the Epidemic diseases Research Group Oxford (ERGO). ERGO is engaged in an international program of clinical and epidemiological research to prepare for and respond to emerging infections that may develop into epidemics or pandemics. ERGO is involved in a number of international projects including the European Commission funded PREPARE project, and the International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC). The group is conducting research on a range of epidemic diseases including Ebola virus disease, bird flu (H5N1 and H7N9), MERS-CoV, and Enterovirus 71. ERGO currently comprises a team of eight people under the leadership of Professor Peter Horby and is funded by the Wellcome Trust, the Medical Research Council, and the European Commission.

In June 2016, Peter became Chair of ISARIC, taking over from outgoing Chair Abdullah Brooks. 

Selected publications 

2017

Sigfrid L, Reusken C, Eckerle I, Nussenblatt V, Lipworth S, Messina J, Kraemer M, Ergonul O, Papa A, Koopmans M, Horby P. Preparing clinicians for (re-) emerging arbovirus infectious diseases in Europe. Clin Microbiol Infect. 2017 Jun 22. pii: S1198-743X(17)30336-1. doi: 10.1016/j.cmi.2017.05.029. Review. Read Abstract | Read More

Wang X, Jiang H, Wu P, Uyeki TM, Feng L, Lai S, Wang L, Huo X, Xu K, Chen E, Wang X, He J, Kang M, Zhang R, Zhang J, Wu J, Hu S, Zhang H, Liu X, Fu W, Ou J, Wu S, Qin Y, Zhang Z, Shi Y, Zhang J, Artois J, Fang VJ, Zhu H, Guan Y, Gilbert M, Horby PW, Leung GM, Gao GF, Cowling BJ, Yu H. Epidemiology of avian influenza A H7N9 virus in human beings across five epidemics in mainland China, 2013-17: an epidemiological study of laboratory-confirmed case series. Lancet Infect Dis. 2017 Aug;17(8):822-832. doi: 10.1016/S1473-3099(17)30323-7. Epub 2017 Jun 2. Read abstract | Read More

Laxminarayan R, Kakkar M, Horby P, Malavige GN, Basnyat B. Emerging and re-emerging infectious disease threats in South Asia: status, vulnerability, preparedness, and outlook. BMJ. 2017 Apr 11;357:j1447. doi: 10.1136/bmj.j1447. Review.

Rojek AM, Horby PW. Offering patients more: how the West Africa Ebola outbreak can shape innovation in therapeutic research for emerging and epidemic infections. Philos Trans R Soc Lond B Biol Sci. 2017 May 26;372(1721). pii: 20160294. doi: 10.1098/rstb.2016.0294. Review. Read Abstract | Read More 

Lee N, Cao B, Ke C, Lu H, Hu Y, Tam CHT, Ma RCW, Guan D, Zhu Z, Li H, Lin M, Wong RYK, Yung IMH, Hung TN, Kwok K, Horby P, Hui DSC, Chan MCW, Chan PKS.IFITM3, TLR3, and CD55 Gene SNPs and Cumulative Genetic Risks for Severe Outcomes in Chinese Patients With H7N9/H1N1pdm09 Influenza. J Infect Dis. 2017 Jul 1;216(1):97-104. doi: 10.1093/infdis/jix235. Read Abstract | Read More

Rojek A, Horby P, Dunning J. nsights from clinical research completed during the west Africa Ebola virus disease epidemic. Lancet Infect Dis. 2017 Sep;17(9):e280-e292. doi: 10.1016/S1473-3099(17)30234-7. Epub 2017 Apr 28. Review. Read Abstract | Read More

Salam AP, Rojek A, Dunning J, Horby PW. Clinical trials of therapeutics for the prevention of congenital Zika virus disease: challenges and potential solutions.Ann Intern Med. 2017 Mar 21. doi: 10.7326/M16-2530. [Epub ahead of print] Read Abstract | Read More

Whitehead J, Horby P. GOST: A generic ordinal sequential trial design for a treatment trial in an emerging pandemic.PLoS Negl Trop Dis. 2017 Mar 9;11(3):e0005439. doi: 10.1371/journal.pntd.0005439. eCollection 2017 Mar 9. Read Abstract | Read More

2016

Nguyen DN, Mai LQ, Bryant JE, Hang NK, Hoa LNM, Nadjm B, Thai PQ, Duong TN, Anh DD, Horby P, et al. Epidemiology and etiology of influenza-like illness in households in Vietnam: it's not all about the kids!Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 82:126-132 Sep 2016 (Journal article) Read Abstract

Koh WM, Bogich T, Siegel K, Jin J, Chong EY, Tan CY, Chen MI, Horby P, Cook AR. The Epidemiology of Hand, Foot and Mouth disease in Asia: a systematic review and analysis
The Pediatric infectious disease journal 35(10):e285-e300 Oct 2016 (Journal articleRead Abstract

Lai S, Qin Y, Cowling BJ, Ren X, Wardrop NA, Gilbert M, Tsang TK, Wu P, Feng L, Jiang H, et al. Global epidemiology of Avian influenza A H5N1 virus infection in humans, 1997-2015: A systematic review of individual case dataThe Lancet. Infectious diseases 16(7):e108-e118 Jul 2016 (Journal article) Read Abstract

Hoa LNM, Mai LQ, Bryant JE, Thai PQ, Hang NK, Yen NT, Duong TN, Thoang DD, Horby P, Werheim HF, et al. Association between hemagglutinin stem-reactive antibiodies and influenza A/H1N1 virus infection during the 2009 pandemicJournal of virology 90(14):6549-6556 Jul 2016 (Journal article) Read Abstract

Horby PW, Rojek A. 2016. Modernising epidemic science: enabling patient-centred research during epidemics. BMC Medicine. 2016:14:12.  DOI: 10.1186/s12916-016-0760-x Read Abstract

Dunning J, Sahr F, Rojek A, Gannon F, Carson G, Idriss B, Massaquoi T, Gandi R, Joseph S, Osman HK, Brooks TJ, Simpson AJ, Goodfellow I, Thorne L, Arias A, Merson L, Castle L, Howell-Jones R, Pardinaz-Solis R, Hope-Gill B, Ferri M, Grove J, Kowalski M, Stepniewsdka K, Lang T, Whitehead J, Olliaro P, Samai M, Horby PW; RAPIDE-TKM Trial Team. 2016. Experimental Treatment of Ebola Virus Disease with TKM-130803: A Single-Arm Phase 2 Clinical Trial. PLoS Med. 2016 Apr 19;13(4):e1001997. doi: 10.1371/journal.pmed.1001997. Read Abstract

Whitehead J, Olliaro P, Lang T, Horby P. 2016. Trial design for evaluating novel treatments during an outbreak of an infectious disease. Clin Trials. 2016 Feb;13(1):31-8. doi: 10.1177/1740774515617740. Epub 2016. Read Abstract | Read more

2015

Cooper BS, Boni MF, Pan-Ngum W, Day NP, Horby PW, Olliaro P, Lang T, White NJ, White LJ, Whitehead J. 2015. Evaluating clinical trial designs for investigational treatments of Ebola virus disease. PLoS Med12 (4), pp. e1001815. Abstract  | Read more

2014

Fonville JM, Wilks SH, James SL, Fox A, Ventresca M, Aban M, Xue L, Jones TC et al. 2014. Antibody landscapes after influenza virus infection or vaccination. Science346 (6212), pp. 996-1000. Read abstract | Read more

Cauchemez S, Ferguson NM, Fox A, Mai LEQ, Thanh LET, Thai PQ, Thhoang DD, Duong TN, Minh Hoa LEN, Tran Hien N, Horby P. 2014. Determinants of influenza transmission in South East Asia: insights from a household cohort study in Vietnam. PLoS Pathog10 (8), pp. e1004310. Read abstract | Read more

2012 

Cauchemez S, Horby P, Fox A, Mai LEQ, Tranh LET, Thai PQ, Hoa LENM, Hien NT, FERGUSON NM. 2012. Influenza infection rates, measurement errors and the interpretation of paired serology.PLoS Pathog8 (12), pp. e1003061. Read abstract | Read more

HORBY P, MAI LQ, FOX A, THAI PQ, THI THU YEN N, THANH LT, LE KHANH HANG N, DUONG TN et al.2012. The epidemiology of interpandemic and pandemic influenza in Vietnam, 2007-2010 American Journal of Epidemiology, 175 (10), pp. 1062-1074. Read abstract | Read more

2011 

CUONG HQ, HIEN NT, DUONG TN, PHONG TV, CAM NN, FARRAR J, NAM VS, THAI KT, HORBY P. 2011. Quantifying the emergence of dengue in Hanoi, Vietnam: 1998-2009. PLoS Negl Trop Dis5 (9), pp. e1322. Read abstract Read more

2010 

HORBY P, SUDOYO H, VIPRAKASIT V, FOX A, THAI PQ, YU H, DAVILA S, HIBBERD M et al. 2010. What is the evidence of a role for host genetics in susceptibility to influenza A/H5N1? Epidemiol Infect138 (11), pp. 1550-1558. Read abstract | Read more

LE QM, WERTHEIM HF, TRAN ND, VAN DOORN HR, NGUYEN TH, HORBY P, VIETNAM H1N1 INVESTIGATION TEAM. 2010. A community cluster of oseltamivir-resistant cases of 2009 H1N1 influenza. N Engl J Med362 (1), pp. 86-87. | Read more

2009

LIEM NT, TUNG CV, HIEN ND, HIEN TT, CHAU NQ, LONG HT, HIEN NT, MAI LEQ et al. 2009. Clinical features of human influenza A (H5N1) infection in Vietnam: 2004-2006. Clin Infect Dis, 48 (12), pp. 1639-1646. Read abstract | Read more

WERTHEIM HF, NGUYEN HN, TAYLOR W, LIEN TT, NGO HT, NGUYEN TQ, NGUYEN BN, NGUYEN HH et al. 2009. Streptococcus suis, an important cause of adult bacterial meningitis in northern Vietnam.PLoS One, 4 (6), pp. e5973. Read abstract Read more

Boni MF, Manh BH, Thai PQ, Farrar J, Hien TT, Hien NT, Van Kinh N, Horby P. 2009. Modelling the progression of pandemic influenza A (H1N1) in Vietnam and the opportunities for reassortment with other influenza viruses. BMC Med, 7 (1), pp. 43. Read abstract Read more

2008

Nguyen TH, Farrar J, Horby P. 2008. Person-to-person transmission of influenza A (H5N1).Lancet, 371 (9622), pp. 1392-1394. | Read more

Le MT, Wertheim HF, Nguyen HD, Taylor W, Hoang PV, Vuong CD, Nguyen HL, Nguyen HH et al. 2008. Influenza A H5N1 clade 2.3.4 virus with a different antiviral susceptibility profile replaced clade 1 virus in humans in northern Vietnam. PLoS One, 3 (10), pp. e3339. Read abstract | Read more

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