Charvy Narain describes how Oxford medics found themselves on the front line
This article discusses the designs used for two such clinical trials which have recruited patients in Liberia and Sierra Leone. General principles are outlined for trial designs intended to be deployed quickly, adapt flexibly and provide results soon enough to influence the course of the current epidemic rather than just providing evidence for use should Ebola break out again. Lessons are drawn for the conduct of clinical research in future outbreaks of infectious diseases, where the sequence of events may or may not be similar to the West African Ebola epidemic. The paper was published in Clinical Trials.
This article describes the treatments tested during the recent Ebola outbreak, it was published in Science on the 31st of December 2015.
Very few treatments have been sucessful in treating Ebola. Convalescent plasma has been used sucessfully to treat a number of diseases, the Ebola Tx consortium examined the utility of using convalescent plasma to treat Ebola patients attending an Ebola Treatment Centre in Guinea.
Could scientists make history and change the way we deal with outbreaks?